|PINA: Protein Interaction Network Analysis platform|
The PINA protein interaction database and Interactome files have been updated. The module collections will be updated in near future.
Protein Interaction Network Analysis (PINA) platform is an integrated platform for protein interaction network construction, filtering, analysis, visualization and management. It integrates protein-protein interaction data from six public curated databases and builds a complete, non-redundant protein interaction dataset for six model organisms. Moreover, it provides a variety of built-in tools to filter and analyze the network for gaining insight into the network.
PINAv2 releases fully annotated modules identified from 6 PINA Interactomes. A new tool is also provided for identifiying enriched modules from users' query proteins.
Cowley, M.J., Pinese, M., Kassahn, K.S., Waddell, N., Pearson, J.V., Grimmond, S.M., Biankin, A.V., Hautaniemi, S. and Wu, J. (2012) PINA v2.0: mining interactome modules. Nucleic Acids Res, 40, D862-865. [Full text]
Wu, J., Vallenius, T., Ovaska, K., Westermarck, J., Makela, T.P. and Hautaniemi, S. (2009) Integrated network analysis platform for protein-protein interactions, Nature methods, 6, 75-77. [Abstract]
Protein-protein interaction data from IntAct, MINT, BioGRID, DIP, HPRD, MIPS/MPact
Protein annotations from UniProt, Ensembl, WormBase
Utilize web services from BioMart